Silver and silver compounds have been registered. All these dossiers are now in the maintenance phase. In 2014, silver was listed on the CoRAP (Community Rolling Action Plan) list for Substance Evaluation for concerns related to environmental behavior and ecotoxicity of nanoforms. The final decision was issued in June 2016 and requested information on ecotoxicity, physico-chemical properties and uses of nanosilver. Furthermore, if any of the ecotoxicity tests indicated a higher toxicity for the nanoform than for ionic silver, information on environmental fate of nanosilver had to be provided. The dossier has been updated in July 2017 with the information on ecotoxicity, physico-chemical properties and uses of nanosilver. Since the ecotoxicity tests did not indicate a higher toxicity for the nanoform than for ionic silver, further fate testing was not needed. The conclusions of the Substance Evaluation drafted by the Netherlands have been available since November 2018.  Substance evaluation – CoRAP.

Silver metal – harmonized classification process

EPMF notes the adoption of the All news – ECHA ( of the European Chemicals Agency’s Risk Assessment Committee (RAC) on silver, which recommends a harmonised human health classification for reproductive toxicity (category 2 – fertility (H361F)) and Specific Target Organ Toxicity – Repeated Exposure (STOT RE category 2 (brain)) for nano-silver, silver metal (massive and powder forms) and a harmonised environmental classification for aquatic acute 1 and aquatic chronic 1 for silver powder and silver nano.

EPMF is disappointed that the RAC chose not to make a differentiation between silver metal (massive and powder) and nanosilver, despite scientific evidence presented to the RAC as part of the opinion making process. Our industry remains convinced that, based on recent scientific studies, a differentiation should be drawn between the behaviour of different forms of silver for human health endpoints and silver metal (massive and powder) should not receive the same harmonised classification for reproductive effects, nor for STOT RE than nanosilver.

We urge the Commission and Member States to take this evidence into account as they consider the RAC’s opinion in their decision-making process.

The RAC’s opinion will be made publicly available by ECHA by the end of the summer. It will be used by the Commission and EU Member States in developing and adopting an adaptation to Annex VI of the Classification, Labeling and Packaging (CLP) Regulation. The change in the harmonised classification of silver is expected to take effect at the beginning of 2026 at the earliest.

Registration and Timeline

Silver and Silver Compounds Inventory
(Including Classifications and ID Cards)

EPMF Silver Working Group

Chair: Clémence Siret (SAFT, France)
Co-Chair: Rob Garrett (Ames Goldsmith, United Kingdom)

Responsible Secretariat Officer(s):
Katrien Arijs, Jelle Mertens & Anissa Alami

Identified uses of Silver

The identified uses of the silver substances registered by the EPMF have been covered in Exposure Scenarios (ES) when needed. These Exposure Scenarios are not only a requirement for the REACH registration dossiers but must also be communicated down the supply chain to downstream users (DU) via the Extended Safety Data Sheets (eSDS).

Once a DU has received the eSDS, they need to:

  • Check whether it covers their use
  • Check whether the conditions of safe use correspond to the operational conditions and risk management measures implemented at their site.

This section of the website has been developed to assist in communication along the supply chain. It provides all EPMF members, downstream users and potential new co-registrants with the most recent list of identified uses and versions of existing DU ES extracted from the chemical safety reports (CSR) of silver and silver compounds covered by the EPMF.

You will find below the list of identified uses (and Exposure Scenarios when relevant) by substance.
Disilver oxide uses
Disilver(1+) sulphate uses
Silver uses
Silver Bromide uses
Silver Carbonate uses
Silver Chloride uses
Silver Iodide uses
Silver Nitrate uses

Further Guidance

If your use is not covered or if you need more information, please do not hesitate to contact us.
ECHA website section for Downstream Users 
(available in 22 EU languages)
Guidance documents drafted by Eurometaux and ECHA